Microbiome Labs Zenbiome™ Sleep

Form/Duration

Study Details and Results

Reference

Bifidobacterium longum

1714® (Zenbiome Cope™ & Sleep™) 4 weeks

Double-blind, randomized,

placebo-controlled, repeated

measures, cross-over design

20 participants

Overall sleep quality and duration of sleep improved significantly in the probiotic treated group during exam stress compared with the placebo treated group.

DOI: 10.1016/ j.bbih.2020.100174

Bifidobacterium longum 1714® and Bifidobacterium longum 35624® (Zenbiome Cope™ & Sleep™)

8 weeks

Open label exploratory study

40 participants

This exploratory open-label study found that 82% of subjects had significantly improved issues after 8 weeks, with 66% of subjects significantly improving after 4-weeks (issue severity score change of ≥ 50) in the moderate to severe group. The combination solution improved each of the individual issues (occasional abdominal discomfort, distension, bowel satisfaction), as well as an improvement in their quality of life. Participants in this group also had a significant improvement in their morning cortisol awakening response, a physiological biomarker of stress, after 4-weeks.

DOI: 10.1111/nmo.14477
Dosing Instructions Zenbiome COPE Ages 8 : Take 1-2 capsules with or without a meal, or as directed by your healthcare practitioner. Zenbiome SLEEP Ages 8 : Take 1 capsule in the evening with or without a meal, or as directed by your healthcare practitioner.

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